GPs usually care for their patients for an extended period of time, therefore, requests to not only discontinue a patient’s treatment but to assist a patient in a suicide are likely to create intensely stressful situations for physicians. However, in order to ensure the best patient care possible, the competent communication about the option of physician assisted suicide as well as the assessment of the origin and sincerity of the request are very important. This is especially true, since patients’ requests (...) for PAS can also be an indicator for unmet needs or concerns. Twenty-three qualitative semi-structured interviews were conducted to in-depth explore this multifaceted, complex topic while enabling GPs to express possible difficulties when being asked for assistance. The analysis of the gathered data shows three main themes why GPs may find it difficult to professionally communicate about PAS: concerns for their own psychological well-being, conflicting personal values or their understanding of their professional role. In the discussion part of this paper we re-assess these different themes in order to ethically discuss and analyse how potential barriers to professional communication concerning PAS could be overcome. (shrink)

Absolute and relative outcome measures measure a treatment’s effect size, purporting to inform treatment choices. I argue that absolute measures are at least as good as, if not better than, relative ones for informing rational decisions across choice scenarios. Specifically, this dominance of absolute measures holds for choices between a treatment and a control group treatment from a trial and for ones between treatments tested in different trials. This distinction has hitherto been neglected, just like the role of absolute and (...) baseline risks in rational decision-making that my analysis reveals. Recognizing both aspects advances the discussion on reporting outcome measures. (shrink)

Food security is becoming an increasingly relevant topic in the Global North, especially in urban areas. Because such areas do not always have good access to nutritionally adequate food, the question of how to supply them is an urgent priority in order to maintain a healthy population. Urban and peri-urban agriculture, as sources of local fresh food, could play an important role. Whereas some scholars do not differentiate between peri-urban and urban agriculture, seeing them as a single entity, our hypothesis (...) is that they are distinct, and that this has important consequences for food security and other issues. This has knock-on effects for food system planning and has not yet been appropriately analysed. The objectives of this study are to provide a systematic understanding of urban and peri-urban agriculture in the Global North, showing their similarities and differences, and to analyse their impact on urban food security. To this end, an extensive literature review was conducted, resulting in the identification and comparison of their spatial, ecological and socio-economic characteristics. The findings are discussed in terms of their impact on food security in relation to the four levels of the food system: food production, processing, distribution and consumption. The results show that urban and peri-urban agriculture in the Global North indeed differ in most of their characteristics and consequently also in their ability to meet the food needs of urban inhabitants. While urban agriculture still meets food needs mainly at the household level, peri-urban agriculture can provide larger quantities and has broader distribution pathways, giving it a separate status in terms of food security. Nevertheless, both possess potential, making them valuable for urban food planning, and both face similar threats regarding urbanisation pressures, necessitating adequate planning measures. (shrink)

In this contribution, Andrew Arato and Jean Cohen’s Populism and Civil Society is confronted with current gender studies research on populism. This research mainly focuses on right-wing populism and highlights strong links between right-wing populists and the religious right, which are to a large degree organized by “anti-gender,” a stance both against social constructivist notions of gender and against basic gender rights, especially in the fields of reproduction and of LGBTIQ concerns. Against the backdrop of this literature, I argue that (...) in Populism and Civil Society, right-wing populist anti-gender politics are not addressed in a way that takes account of their full complexity; and that these politics furthermore suggest to treat right-wing populism and left-wing populism as phenomena that do not only differ in content, but also in form. (shrink)

This article considers the sexual politics of animal evidence in the context of German sexology around 1920. In the 1910s, the German-Jewish geneticist Richard B. Goldschmidt conducted experiments on the moth Lymantria dispar, and discovered individuals that were no longer clearly identifiable as male or female. When he published an article tentatively arguing that his research on ‘intersex butterflies’ could be used to inform concurrent debates about human homosexuality, he triggered a flurry of responses from Berlin-based sexologists. In this article, (...) I examine how a number of well-known sexologists affiliated with Magnus Hirschfeld, his Scientific-Humanitarian Committee, and later his Institute of Sexology attempted to incorporate Goldschmidt’s experiments into their sexological work between 1917 and 1923. Intersex butterflies were used to discuss issues at the heart of German sexology: the legal debate about the criminalisation of homosexuality under paragraph 175; the scientific methodology of sexology, caught between psychiatric, biological, and sociological approaches to the study of sexual and gender diversity; and the status of sexology as natural science, able to contribute knowledge about the sexual Konstitution of the organism. This article thus shows that butterfly experiments function as important and politically charged evidence for a discussion at the heart of the sexological project of those involved in the founding of the Institute of Sexology: the question of the nature and naturalness of homosexuality and its political consequences. In doing so, this article makes a case for paying attention to non-human actors in the history of sexology. (shrink)

During the last twenty years, Kant's theory of biology has increasingly attracted the attention of scholars and developed into a field which is growing rapidly in importance within Kant studies. The volume presents fifteen interpretative essays written by experts working in the field, covering topics from seventeenth- and eighteenth-century biological theories, the development of the philosophy of biology in Kant's writings, the theory of organisms in Kant's Critique of the Power of Judgment, and current perspectives on the teleology of nature.

Advance directives are written documents that give patients the opportunity to communicate their preferences regarding treatments they do or do not want to receive in case they become unable to make decisions. Commonly used pre-printed forms have different formats. Some offer space for patients to appoint a surrogate decision maker, and/or to determine future medical treatments and/or give a statement of personal values. So far it is unknown which forms GPs preferably use and why they decide to do so. 23 (...) semi-structured interviews with GPs were analysed using content analysis. Interviewees mainly use short templates and medium length templates with checkboxes to indicate patients’ preferences in regards to life prolonging measures. Especially when patients faced the progression of a disease, participants use the latter version. Only then, the interviewees remarked, patients are capable to rate concrete situations reliably. GPs also realize the importance of the verbal assessment of patients’ preferences; however they rarely keep a written form of the conversation. Some GPs hand out one or more templates and ask their patients to read and think about them at home with the option to talk to them about it later on, while others prefer their patients to fill them out alone at home. Regardless of template usage, most GPs emphasize that ADs require regular updates. GPs tend to see standardized advance directives mainly as a tool to start a conversation with their patients and to identify their real preferences and values. When the patient is still not facing the progression of an already existing disease it could be sufficient to only appoint a surrogate decision maker instead of creating a full AD. However, in all other situations, appointing a surrogate decision maker should be backed up by a written statement of a patient’s general values. Patients and their relatives should always have the opportunity to ask their GP for medical advice when drafting an AD. It is crucial to regularly verify and update existing ADs within the course of a disease. (shrink)

Articles on different religious philosophies of pre-colonial Bengal, India.

The human being as a constituted objectivity is a fragile ‘figure’ who lives in through their individual and shared experience. As a constituted objectivity, it influences our experiences, actions and the constitution of our community. Nevertheless, it appears to us, who actually constitute it, as a completely independent and immutable object, as a mere fact our experience has to comply with, and as a normative representation of the human being. This paper inquires - from a phenomenological point of view - (...) about the structure that underlies the norm at work in our experience, as well as in the high- and low-level dimensions of the intersubjective community. Indirectly, such a structure can be identified through the connection between Husserl’s understanding of normality and objectivity. My claim is that normativity can be understood as a necessary function and thus can be distinguished from objectivity and normality. Normativity appears, therefore, as a function of objectivity, which allows one to distinguish the latter from normality. As such, normativity should not be confused with an active agreement or regulation, but rather identified as a necessary constitutive structure arising from experiential intersubjective sense-borrowing performance. At the same time, due to its connection to objectivity, normativity also appears to strongly influence the social production of validity, therefore being endorsed by institutions. (shrink)

ZusammenfassungDer Artikel skizziert die Grundlagen einer neuen Subdisziplin innerhalb der Religionswissenschaft, der Religionsethologie. Religionsethologie lässt sich letztlich auf Charles Darwin selbst zurückführen, der bereits in seinem Buch The expression of the emotions in man and animals belegen konnte, dass jede Form von Verhalten für das Überleben der Art genau so wichtig ist wie die Adaptation des Phänotypus. In den Geisteswissenschaften wurde der Darwinsche Ansatz sofort aufgegriffen und von bedeutenden Forschern wie Karl Meuli, Aby Warburg und in jüngerer Zeit von Roy (...) Rappaport, Marvin Harris und anderen aufgegriffen und fruchtbar gemacht, indem sie einerseits religiöse Universalien herausarbeiten, andererseits aber auch die Grundzüge einer religiösen Evolution darstellen konnten. Religion ist demnach tief in der Biologie des Menschen verwurzelt und kann demzufolge auch unter biologischen Gesichtspunkten erforscht werden. (shrink)

Background:More and more adults in their fifties and sixties are confronted with the need to support their ageing parents. Although many aspects of filial caregiving have been researched, a well-documented and comprehensive overview of the caregiving experience is lacking.Aim:This study aims for a better understanding of the caregiving experience of adult children by generating an overview of main themes in international research.Method:A literature review of qualitative studies, focusing on the experiences of adult children caring for their ageing parents, was performed. (...) The electronic EBSCO databases Academic Search Premier, CINAHL and PsycINFO, and Google Scholar were searched to identify relevant qualitative studies published between 2000 and 2017. The ‘SPIDER’ eligibility criteria directed the approach. The quality of studies included was screened with the assessment sheet designed by Hawker and colleagues. The experiences reported were analysed and themes were synthesized.Ethical consideration:Ethical requirements were respected in every phase of the research process.Findings:Nineteen qualitative studies met the inclusion criteria. The quality of the relationship with the parent appears to be an important determinant of the children’s caregiving experience. Within this context, three themes were found: caregiving as an emotional rollercoaster, a normatively demanding experience and an opportunity for personal development.Discussion:Children caring for their ageing parents have to deal with a wide range of contradicting and conflicting norms and values. Implications for healthcare professionals and future research have been discussed.Conclusion:Caring for ageing parents is a continuous quest for giving the best possible care and living up to one’s personal values, within the context of the parent’s declining health. Professionals who support filial caregivers should address not only practical responsibilities but also the normative questions and moral considerations caregivers are dealing with. (shrink)

This article is focused on the differences between shame and guilt examined through a psychological perspective. The purpose of this analysis developed here is to attain conceptual clarity about what is distinctive about shame and guilt. We claim that shame is erroneously included in the category of “moral emotions” and that, paradoxically, there is nothing moral in it. To this end, we emphasize that shame is produced by the failure to achieve a certain minimum, which is social in its nature. (...) It is therefore connected with low demands on one’s self and low self-esteem. Guilt, on the other hand, is based on the failure to achieve a subjective maximum and an ideal, so it tends to be observed in personalities that exhibit high demands upon themselves and a high self-esteem. (shrink)

Over the last few years, the idea that we live in a globalized world has significantly gained ground. Across various disciplines, this had led to severe critiques not only of methodological nationalism, but also of methodological Eurocentrism. But what does it mean to leave Eurocentrism behind? What kind of theorizing can and should we engage in when we attempt to provincialize, decenter, or even decolonize our thinking? This article distinguishes, presents, and critically discusses four trajectories beyond Eurocentrism in political and (...) social theory: enlarging the canon, inter-contextual dialogue, taking the impacts of European colonialism and imperialism into account, as well as shifts in theoretical agenda setting. It argues that if political and social theory truly attempts to transcend methodological Eurocentrism, it must not only bring in non-Western thought, but must also critically address both discursive and institutional aspects of global power relations. (shrink)

Ein textnaher, fortlaufender Kommentar zu Kants Lehre von organisierten Wesen in der „Kritik der Urteilskraft“ ist ein Desiderat sowohl der Kantforschung als auch der Philosophie und Geschichte der Lebenswissenschaften. Auch gibt es bisher nur wenige Lesarten, die Kants Philosophie der Biologie im Ganzen erschließen und versuchen, sie in die vielschichtigen historischen Kontexte der frühneuzeitlichen Naturforschung einzuordnen. Das vorliegende Buch schließt diese Lücken. Es verteidigt die Thesen, dass Kant organisierte Wesen durch drei Arten von Kräften und Gesetzen charakterisiert – durch mechanische, (...) physisch teleologische und moralteleologische Krätfe und Gesetze – deren Vereinbarkeit im Bewusstsein des Menschen, und in der Erfahrungswelt, so, wie sie dem Menschen erscheint, auf der regulativen Idee ihrer Einheit im schöpferischen, theoretisch praktischen Bewusstsein Gottes beruht. Kants Lehre von organisierten Wesen kann als Verbindung einer gemäßigten, weder animalkulistisch noch ovistisch vereinseitigten, Präformationslehre mit einer vitalistischen Spielart der Epigenesislehre verstanden werden. – Weiterführende und provokative Einsichten für eine der bewegtesten Debatten der gegenwärtigen Kantforschung. (shrink)

Animal, protist and viral messenger RNAs (mRNAs) are most prominently modified at the beginning by methylation of cap‐adjacent nucleotides at the 2′‐O‐position of the ribose (cOMe) by dedicated cap methyltransferases (CMTrs). If the first nucleotide of an mRNA is an adenosine, PCIF1 can methylate at the N6‐position (m6A), while internally the Mettl3/14 writer complex can methylate. These modifications are introduced co‐transcriptionally to affect many aspects of gene expression including localisation to synapses and local translation. Of particular interest, transcription start sites (...) of many genes are heterogeneous leading to sequence diversity at the beginning of mRNAs, which together with cOMe and m6Am could constitute an extensive novel layer of gene expression control. Given the role of cOMe and m6A in local gene expression at synapses and higher brain functions including learning and memory, such code could be implemented at the transcriptional level for lasting memories through local gene expression at synapses. (shrink)